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Table 6 Predictors of lung transplant-free survival after surgical lung biopsy in patients with IPF (after excluding patient who developed lung cancer post-biopsy)

From: Digital quantification of p16-positive foci in fibrotic interstitial lung disease is associated with a phenotype of idiopathic pulmonary fibrosis with reduced survival

Cox proportional hazard analysis

Hazard ratio

C.I

p value

p16 > 2.1 foci per 100 mm.2 of lung tissue

2.40

1.07–5.51

0.0331

Antifibrotic treatment*

0.28

0.10–0.66

0.0029

  1. N = 46. Multi-variate analysis. Age, gender, BMI, FVC (% pred) and DLCO (% pred) were not significant
  2. *Pirfenidone or nintedanib