From: Digital quantification of p16-positive foci in fibrotic interstitial lung disease is associated with a phenotype of idiopathic pulmonary fibrosis with reduced survival
Cox proportional hazard analysis
Hazard ratio
C.I
p value
p16 > 2.1 foci per 100 mm.2 of lung tissue
2.40
1.07–5.51
0.0331
Antifibrotic treatment*
0.28
0.10–0.66
0.0029