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Table 4 Top 5 gene-sets significantly enriched in the fibrotic areas vs normal-looking areas group (GSEA)

From: Digital quantification of p16-positive foci in fibrotic interstitial lung disease is associated with a phenotype of idiopathic pulmonary fibrosis with reduced survival

Gene Set

NES

p value

q value

Regulation of receptor-mediated endocytosis

2.07

0.000

0.028

Positive regulation of receptor-mediated endocytosis

2.03

0.000

0.035

Dilatation of the cerebral artery

2.02

0.000

0.025

Hyperextensible skin

2.01

0.000

0.023

Aortic aneurysm

1.95

0.000

0.062

  1. The positive enrichment score indicated a correlation with the fibrotic areas microenvironment group
  2. NES normalized enrichment score
  3. q value: false discovery ratio
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Respiratory Research

ISSN: 1465-993X

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