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Table 2 Histopathologic characteristics of fibrosing ILD and associated p16 expression

From: Digital quantification of p16-positive foci in fibrotic interstitial lung disease is associated with a phenotype of idiopathic pulmonary fibrosis with reduced survival

Diagnosis

p16-low (%)

p16-high (%)

IPF

31 (60)

21 (40)

NSIP

16 (100)

0 (0)

Unclassifiable

10 (91)

1 (9)

Chronic HP

6 (100)

0 (0)

Smoking-related

1 (100)

0 (0)

  1. Cases were subclassified into p16-low (≤ 2.1 foci per 100 mm2 of lung tissue) and p16-high (> 2.1 foci per 100 mm2 of lung tissue)
  2. IPF idiopathic pulmonary fibrosis, NSIP nonspecific interstitial pneumonia, HP hypersensitivity pneumonitis
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Respiratory Research

ISSN: 1465-993X

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