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Table 1 Patients’ characteristics at the time of surgical lung biopsy and outcomes

From: Digital quantification of p16-positive foci in fibrotic interstitial lung disease is associated with a phenotype of idiopathic pulmonary fibrosis with reduced survival

Diagnosis

n (%)

IPF

52 (60)

NSIP

16 (19)

Unclassifiable

11 (13)

Chronic HP

6 (7)

Smoking-related

1 (1)

Demographics/lung function

Mean ± SD

Age (years)

62 ± 10

Male / Female (% male)

48 / 38 (56%)

BMI (kg/m.2)

30 ± 6

Pack-years

24 ± 19

FVC (% predicted)

75 ± 19

TLC (% predicted)

70 ± 15

DLCO (% predicted)

48 ± 17

Radiographic patterns

(%)

Probable UIP

37 (43)

Indeterminate for UIP

29 (34)

Inconsistent with UIP

20 (23)

HRCT visual fibrosis score

20 ± 8

Outcomes

Mean ± SD

Post-biopsy follow-up

34 ± 35

Alive / transplanted / died

31 / 13 / 42

  1. IPF idiopathic pulmonary fibrosis, NSIP nonspecific interstitial pneumonia, HP hypersensitivity pneumonitis, BMI body mass index, FVC forced vital capacity, TLC total lung capacity. DLCO diffusion lung capacity for carbon monoxide, UIP usual interstitial pneumonia