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Table 4 Risk factors for pneumothorax in patients with RA-ILD in the AMC cohort

From: Pleuroparenchymal fibroelastosis in rheumatoid arthritis-associated interstitial lung disease

Variables

Unadjusted analysis

Multivariable analysis

HR

95% CI

p-value

HR

95% CI

p-value

Age

1.003

0.962–1.047

0.879

   

Men

2.684

1.102–6.539

0.030

0.572

0.083–3.948

0.571

Ever-smokers

3.119

1.248–7.791

0.015

6.114

0.796–46.945

0.082

BMI

0.900

0.79–1.040

0.152

   

FVC

0.986

0.961–1.012

0.286

   

DLCO

0.968

0.945–0.992

0.008

0.968

0.944–0.993

0.011

TLC

0.990

0.963–1.019

0.500

   

RV

0.984

0.960–1.008

0.198

   

UIP-like pattern on HRCT

3.630

0.487–27.071

0.209

   

PPFE

6.876

2.295–20.595

0.001

10.046

3.207–31.469

 < 0.001

Corticosteroid ± IM

0.550

0.186–1.627

0.280

   
  1. RA rheumatoid arthritis, ILD interstitial lung disease, HR hazard ratio, CI confidence interval, BMI body mass index, FVC forced vital capacity, DLco diffusing capacity for carbon monoxide, TLC total lung capacity, RV residual volume, UIP usual interstitial pneumonia, PPFE pleuroparenchymal fibroelastosis, IM immunosuppressant