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Table 2 Clinical features before bronchoscopy in total and propensity score-matched patients

From: Association between oxygen saturation level during bronchoscopy and post-bronchoscopy adverse events: a retrospective cohort study

  Total population Propensity score-matched population
High oxygen saturation group (n = 458) Low oxygen saturation group (n = 111) P-value High oxygen saturation group (n = 222) Low oxygen saturation group (n = 111) Standardized differences
Symptoms, n (%)
 Chronic bronchitis 79 (17.2) 13 (11.7) 0.201 28 (12.6) 13 (11.7) 0.027
 Chronic cough 87 (19.0) 14 (12.6) 0.150 41 (18.5) 14 (12.6) 0.162
 Hemoptysis 54 (11.8) 11 (9.9) 0.695 24 (10.8) 11 (9.9) 0.029
Pulmonary function testa
 FVC, L, mean (± SD) 2.8 (0.6) 2.8 (0.6) 0.947 2.9 (0.6) 2.8 (0.6) 0.093
 FVC, %, mean (± SD) 85.1 (13.5) 87.9 (13.5) 0.054 87.7 (11.5) 87.9 (13.5) 0.013
 FEV1, L, mean (± SD) 2.06 (0.5) 2.0 (0.4) 0.489 2.11 ± 0.5) 2.0 (0.4) 0.185
 FEV1, %, mean (± SD) 89.5 (16.7) 91.4 (16.9) 0.283 92.9 (14.7) 91.4 (17.0) 0.097
 FEV1/FVC, %, mean (± SD) 73.8 (8.9) 72.9 (8.1) 0.338 74.3 (7.6) 72.9 (8.1) 0.175
 BDR, %, median (IQR) 2.0 (0–4.0) 2.0 (0–3.0) 0.351 2.0 (0–4.0) 2.0 (0–3.0) 0.068
 DLCO, %, mean (± SD) 88.6 (29.6) 87.3 (24.8) 0.787 94.4 (26.0) 87.3 (24.8) 0.280
 DLCO/VA, %, mean (± SD) 86.2 (29.4) 88.6 (18.4) 0.615 92.5 (26.0) 88.6 (18.5) 0.179
Clinically suspected diagnosis, n (%)
 Aspiration pneumonia 120 (26.2) 28 (25.2) 0.929 59 (26.6) 28 (25.2) 0.031
 Atypical pneumonia 41 (9.0) 18 (16.2) 0.038 21 (9.5) 18 (16.2) 0.202
 Lung malignancy 121 (26.4) 30 (27.0) 0.992 59 (26.6) 30 (27.0) 0.010
 Mycobacterial infection 176 (38.4) 35 (31.5) 0.215 81 (36.5) 35 (31.5) 0.105
 Lung abscess 21 (4.6) 5 (4.5) 1.000 10 (4.5) 5 (4.5)  < 0.001
 Interstitial lung disease 22 (4.8) 7 (6.3) 0.685 13 (5.9) 7 (6.3) 0.019
 Endobronchial lesion 111 (24.2) 16 (14.4) 0.036 45 (20.3) 16 (14.4) 0.155
Combined acute medical conditions, n (%)
 Acute decompensated heart failure 35 (7.6) 11 (9.9) 0.554 20 (9.0) 11 (9.9) 0.031
 Acute coronary syndrome 4 (3.6) 9 (2.0) 0.495 8 (3.6) 4 (3.6)  < 0.001
 Pneumothorax 17 (3.7) 1 (0.9) 0.224 7 (3.2) 1 (0.9) 0.160
 Pleural effusion 133 (29.0) 28 (25.2) 0.495 61 (27.5) 28 (25.2) 0.051
Surrogates for respiratory failure       
 Desaturation event, n (%) 90 (19.7) 34 (30.6) 0.017 60 (27.0) 34 (30.6) 0.080
 Oxygen demand, L/min, median (IQR) 0 (0–0) 0 (0–1.0) 0.699 0 (0–0) 0 (0–1.0) 0.061
 SF ratio, mean (± SD) 451.5 (53.6) 426.2 (66.6)  < 0.001 439.5 (68.2) 426.2 (66.6) 0.197
 ROX index, mean (± SD) 22.6 (2.8) 21.6 (3.2)  < 0.001 22.1 (3.5) 21.6 (3.2) 0.153
  1. Data are expressed as mean (± standard deviation), median (IQR), or number (percentage)
  2. FVC forced vital capacity; FEV1 forced expiratory volume in one second; BDR bronchodilator test; DLCO diffusion capacity of the lung for carbon monoxide; DLCO/VA diffusion capacity of the lung for carbon monoxide per unit alveolar volume; SD standard deviation; IQR interquartile range
  3. aBronchodilator response was assessed in 342 patients, and DLCO was assessed in 360 patients