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Table 3 Comparison of standardised 3D-CT LV in patients with IPF at diagnosis and at AE

From: Standardised 3D-CT lung volumes for patients with idiopathic pulmonary fibrosis

Standardised 3D-CT LV, %

IPF at diagnosis (n = 61)

AE-IPF Hamamatsu cohort (n = 61)

AE-IPF Seirei cohort (n = 50)

Total lung

100.2 [85.3–114.0]

74.4 [66.5–84.5]*

75.4 [63.1–93.2]*

 Right lung

55.6 [50.2–63.3]

43.6 [35.5–50.6]*

42.9 [35.9–51.5]*

  Right upper lobe

25.0 [22.0–28.3]

18.5 [14.7–23.4]*

18.3 [15.6–22.9]*

  Right middle lobe

12.3 [10.8–15.4]

10.2 [7.7–12.6]*

8.7 [7.0–10.7]*

  Right lower lobe

17.9 [14.6–21.0]

13.4 [11.7–15.6]*

13.7 [11.6–15.9]*

 Left lung

44.8 [36.1–50.5]

31.9 [25.4–37.1]*

32.1 [26.3–42.3]*

  Left upper lobe

27.6 [23.6–34.1]

19.5 [16.0–22.0]*

18.7 [13.8–24.1]*

  Left lower lobe

16.3 [12.4–20.8]

11.6 [9.6–14.1]*

14.2 [11.4–17.1]*

Upper lobes

51.9 [44.2–60.1]

38.4 [32.8–44.2]*

35.5 [28.6–48.2]*

Lower lobes

34.2 [26.9–41.1]

25.2 [21.3–29.7]*

26.6 [23.2–32.8]*

  1. 3D-CT 3-dimensional computed-tomography, LV lung volume, IPF idiopathic pulmonary fibrosis, AE acute enervation
  2. *p < 0.001 (compared with that at IPF diagnosis)