From: An algorithm to identify cases of pulmonary arterial hypertension from the electronic medical record
Test Characteristics | RF Algorithm in SD | RF Algorithm SD Non-Cases | French Registry | REVEAL | UK-Ireland Registry |
---|---|---|---|---|---|
n | 265 | 2,270,971 | 674 | 2525 | 482 |
Age (years) | 52.0 (13.7) | 52.0 (21.4) | 50.0 (15.0) | 50.1 (14.4) | 50.1 (17.1) |
Sex, % female (n) | 72.1% (191) | 54.2% (1,253,660) | 65.3% | 79.5% | 69.9% |
Comorbidities | |||||
CTD (n) | 33.2% (88) | 2.0% (465) | 15.3% | 25% | – |
CHD (n) | 19.2% (51) | 0.9% (19,950) | 11.3% | 10% | – |
Medications | |||||
ERA (n) | 70.6% (187) | < 0.1% (26) | – | 47% | 44.2% |
GS stimulators (n) | 1.5% (4) | < 0.1% (9) | – | – | – |
PDE5 inhibitors (n) | 84.2% (223) | 0.4% (9,224) | – | 49% | 29.2% |
Prostanoids (n) | 63.0% (167) | < 0.1% (2) | – | – | 18.8% |
Hemodynamics (n = 189) | (n = 8806) | ||||
RA pressure (mmHg) | 10.1 (6.0) | 8.8 (8.3) | 8 (5.) | 9.3 (5.6) | 10.1 (6.0) |
Mean PA (mmHg) | 49.8 (13.6) | 27.7 (11.7) | 55 (15) | 50.7 (13.6) | 54.1 (13.9) |
PWP (mmHg) | 11.3 (6.1) | 15.5 (8.3) | 8.0 (3) | 9.1 (3.5) | 9.2 (3.5) |
CO, Fick (L/min) | 4.8 (2) | 5.6 (3.7) | – | – | 4.0 (1.5)** |
CO, TD (L/min) | 4.8 (1.7) | 5.1 (2.4) | – | – | 4.0 (1.5)** |
CI, Fick (L/min/M2) | 2.5 (1.0) | 2.9 (2.7) | 2.9 (0.9)* | 2.4 (0.8)* | 2.1 (6.3) |
CI, TD (L/min/M2) | 2.5 (0.8) | 2.6 (2.2) | 2.9 (0.9)* | 2.4 (0.8)* | 2.1 (6.3) |
PVR (Wood units) | 9.9 (5.9) | 2.6 (2.5) | *** | *** | 12.8 (6.3) |