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Table 4 Diagnostic performance of the scoring system based on nomogram in differentiating TPE from non-TB BPE in the training set and validation sets

From: Development and validation of a prediction model for tuberculous pleural effusion: a large cohort study and external validation

Variables Training set Internal validation set External validation set
AUC (95%CI) 0.937 (0.917–0.957) 0.934 (0.902–0.966) 0.941 (0.891–0.991)
Sensitivity (95%CI) 89.0% (84.8–92.3%) 88.7% (81.8–93.7%) 93.6% (84.3–98.2%)
Specificity (95%CI) 89.5% (85.8–92.4%) 90.3% (84.0–94.7%) 87.5% (74.8–95.3%)
PLR (95%CI) 8.5 (6.2–11.4) 9.1 (5.4–15.4) 7.5 (3.5–15.9)
NLR (95%CI) 0.12 (0.09–0.21) 0.13 (0.08–0.18) 0.07 (0.03–0.20)
PPV (95%CI) 87.2% (83.4–90.2%) 89.4% (83.4–93.4%) 90.6% (82.0–95.3%)
NPV (95%CI) 91.0% (87.9–93.3%) 89.6% (84.0–93.4%) 91.3% (80.2–96.5%)
  1. TPE tuberculous pleural effusion, BPE benign pleural effusion, AUC area under curve, CI confidence interval, PLR positive likelihood ratio, NLR negative likelihood ratio, PPV positive predictive value, NPV negative predictive value