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Fig. 6 | Respiratory Research

Fig. 6

From: Exogenous leptin enhances markers of airway fibrosis in a mouse model of chronic allergic airways disease

Fig. 6

Sex differences. A, B Comparison of changes in total lung resistance between treatments in A males and B females, n = 3–8 mice per group. *p < 0.05 PBS+saline vs. PBS+leptin, #p < 0.05 PBS+leptin vs. HDM+leptin, ^p < 0.05 PBS+saline vs. HDM+saline by two-way ANOVA with Tukey’s post hoc test. C Sex differences in airway mucus were evaluated by scoring of peribronchial mucus in PAS-stained lungs, n = 6–9 mice per group, 9 airways per mouse. D Sex differences in TGB-β1 levels in BAL evaluated by ELISA, n = 5–9 mice per group. *p < 0.05 **p < 0.01, ***p < 0.001, ****p < 0.0001 vs. corresponding PBS treatment by three-way ANOVA with Šidák correction, ^p < 0.05 vs. male of the same treatment by three-way ANOVA with Šidák correction

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