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Fig. 5 | Respiratory Research

Fig. 5

From: Exogenous leptin enhances markers of airway fibrosis in a mouse model of chronic allergic airways disease

Fig. 5

Changes in lung mechanics. A, B Change in total lung resistance in response to methacholine, both A absolute and B percent change, n = 11–16 mice per group. ***p < 0.001 PBS+leptin vs. HDM+leptin and *p < 0.05 PBS+saline vs. PBS+leptin by two-way ANOVA with Tukey’s post hoc test. C, D Change in tissue damping in response to methacholine, both C absolute and D percent change, n = 11–16 mice per group. *p < 0.05 PBS+leptin vs. HDM+leptin and ****p < 0.0001 PBS+leptin vs. HDM+leptin by two-way ANOVA with Tukey’s post hoc test

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