Fig. 3

Changes in peribronchial inflammation and BAL cellularity. A Representative images of H&E-stained mouse lung sections taken at ×100 magnification, scale bar = 250 μm. B Mean peribronchial inflammation score of H&E-stained lung sections, n = 12–18 mice per group, 9 airways per mouse. C–F Relative numbers of C eosinophils, D neutrophils, E lymphocytes, and F macrophages in BAL were evaluated, n = 8–12 mice per group. G IL-5 and H CCL11 levels measured in BAL fluid, n = 12–18 mice per group. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 vs. corresponding PBS treatment; ^#p < 0.05, ^####p < 0.0001 vs. HDM+saline by two-way ANOVA with Šidák correction