Module | Co-expression Network Hub Gene | Number of Interactions | Number of Annotation Clusters | Top Functional Annotation Clusters within Co-expression Network |
---|---|---|---|---|
M1 | CIT, Citron Rho-Interacting Serine/Threonine Kinase | 1350 | 54 | rRNA Processing, mRNA splicing, RNA binding, ATP binding, viral nucleoprotein |
LGALS9, Galectin | 444 | 43 | viral transcription, Cell–cell adhesion, nucleotide binding, protein folding, endoplasmic reticulum, mitochondrion, ER-Golgi transport | |
VCAM1, Vascular Cell Adhesion Molecule 1 | 412 | 29 | cell–cell adhesion, RNA-binding, protein folding, actin binding | |
ISG15, ISG15 Ubiquitin-like Modifier | 164 | 19 | cadherin binding, ATP-binding, glycolytic process, actin binding, MHC class II protein complex binding | |
SOCS1, Suppressor of Cytokine Signaling 1 | 86 | 24 | ATP binding, MAPK cascade, tyrosine-protein kinase, JAK/Stat signaling pathway | |
M4 | HCK, HCK Proto-Oncogene, Src Family Tyrosine Kinase | 67 | 14 | ATP binding, PI3K-Akt signaling, unfolded protein response, protein tyrosine kinase activity |
TNFAIP3, TNF Alpha Induced Protein 3 | 50 | 17 | NFκB signaling, toll like receptor signaling, ubiquitin-protein transferase activity, CD40 receptor complex, TNF signaling | |
BDKRB1, Bradykinin Receptor 1 | 30 | 2 | Membrane, endoplasmic reticulum | |
MYH11, Myosin Heavy Chain 11 | 19 | 5 | cytoskeleton, motor protein, myosin, cell division | |
CCL5, C–C Motif Chemokine Ligand 5 | 15 | 3 | chemokine activity, leukocyte chemotaxis |