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Fig. 6 | Respiratory Research

Fig. 6

From: Th1 cytokines synergize to change gene expression and promote corticosteroid insensitivity in pediatric airway smooth muscle

Fig. 6

Differential gene expression and pathway analysis in response to TNFα/IFNγ and fluticasone propionate (FP). Volcano plot for differentially expressed genes in A TNFα/IFNγ vs. control, B TNFα/IFNγ vs. TNFα, C TNFα/IFNγ vs. IFNγ, D FP + TNFα/IFNγ vs. control, E FP + TNFα/IFNγ vs. TNFα/IFNγ are displayed. The total number of significantly up-regulated and down-regulated genes are stated. Volcano plots are represented by plotting -log10 (adjusted p value) and log2 fold change. Top 10 F KEGG and Reactome terms and G enriched transcription factor motifs. Enrichment is represented by plotting -log10 (adjusted p value)

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