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Fig. 5 | Respiratory Research

Fig. 5

From: Th1 cytokines synergize to change gene expression and promote corticosteroid insensitivity in pediatric airway smooth muscle

Fig. 5

Differential gene expression and pathway analysis in response to IFNγ and fluticasone propionate (FP). Volcano plots for differentially expressed genes in A IFNγ vs. control, B FP + IFNγ vs. control, and C FP + IFNγ vs. IFNγ are displayed. The total number of significantly up-regulated and down-regulated genes are stated. Volcano plots are represented by plotting -log10 (adjusted p value) and log2 fold change. Top 10 D KEGG and Reactome terms and E enriched transcription factor motifs. Enrichment is represented by plotting -log10 (adjusted p value)

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