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Fig. 2 | Respiratory Research

Fig. 2

From: Th1 cytokines synergize to change gene expression and promote corticosteroid insensitivity in pediatric airway smooth muscle

Fig. 2

Principal Component Analysis of RNA-seq data. A The Eigencor plot shows effect of age, gender, fluticasone propionate (FP) and cytokine treatment on principal components. Significant effects were observed cytokine treatment (PC1), gender and age (PC2), and FP treatment (PC3). The scale bar represents Eigenvalues (− 1 to 1, with 0 having no correlation). adjusted p value < 0.05, ***indicates significant effect. B Percentage of variation for each principal component is shown in the Scree plot. C Principal Component Analysis plot for PC1 vs PC2, which together account for ~ 70% variation, is plotted

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