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Fig. 3 | Respiratory Research

Fig. 3

From: NecroX-5 ameliorates bleomycin-induced pulmonary fibrosis via inhibiting NLRP3-mediated epithelial–mesenchymal transition

Fig. 3

NecroX-5 inhibited NLRP3 activation and the TGF-β1/Smad2/3 pathway in BLM-treated mice. A NLRP3 mRNA expression in lung tissue. B ASC mRNA expression in lung tissue. C Caspase-1 mRNA expression in lung tissue. D The expression of cleaved caspase 1 in lung tissue. E Lung tissue levels of TGF-β1. F Protein expression of phospho (p-)Smad2/3. G Protein expression of Slug. *P < 0.05. vs. controls; &P < 0.05 vs. BLM

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Respiratory Research

ISSN: 1465-993X

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