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Fig. 2 | Respiratory Research

Fig. 2

From: NecroX-5 ameliorates bleomycin-induced pulmonary fibrosis via inhibiting NLRP3-mediated epithelial–mesenchymal transition

Fig. 2

NecroX-5 inhibited the EMT process in pulmonary epithelial cells exposed to BLM. A The morphology of MLE-12 cells. B Cytokeratin-8 mRNA expression in MLE-12 cells. C E-cadherin mRNA expression in MLE-12 cells. D α-SMA mRNA expression in MLE-12 cells. E Vimentin mRNA expression in MLE-12 cells. F The expression of epithelial markers and mesenchymal markers in MLE-12 cells was confirmed by immunostaining. G The morphology of BEAS-2B cells. H Cytokeratin-8 mRNA expression in BEAS-2B cells. I E-cadherin mRNA expression in BEAS-2B cells. J α-SMA mRNA expression in BEAS-2B cells. K Vimentin mRNA expression in BEAS-2B cells. L The expression of epithelial markers and mesenchymal markers in BEAS-2B cells was confirmed by immunostaining. *P < 0.05, vs. controls; &P < 0.05 vs. BLM

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Respiratory Research

ISSN: 1465-993X

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