Table 1 Clinical characteristics of TCGA and GEO dataset
Variable | TCGA-LUAD dataset (N = 477) N(%) | GEO LUAD dataset (N = 318) | ||
|---|---|---|---|---|
GSE30219 N(%) | GSE37745 N(%) | GSE50081 N(%) | ||
Age | ||||
< 68 | 261 (54.7) | 61 (73.5) | 71 (67.0) | 48 (37.2) |
≥68 | 216 (45.3) | 22 (26.5) | 35 (33.0) | 81 (62.8) |
Gender | ||||
Female | 257 (53.9) | 18 (21.7) | 60 (56.6) | 62 (48.1) |
Male | 220 (46.1) | 65 (78.3) | 46 (43.4) | 67 (51.9) |
Stage | ||||
I | 4 (0.8) | NA | NA | NA |
IA | 124 (26.0) | NA | NA | 37 (28.7) |
IB | 125 (26.2) | NA | NA | 56 (43.4) |
II | 191 (40.0) | NA | NA | NA |
IIA | 7 (5.4) | |||
IIB | 29 (22.5) | |||
III | NA | NA | NA | 0 (0) |
IV | 25 (5.2) | NA | NA | 0 (0) |
Unknow | 8 (1.7) | NA | NA | 0 (0) |
T | ||||
T1 | 159 (33.3) | 69 (83.1) | NA | 44 (34.1) |
T2 | 254 (53.2) | 12 (14.5) | NA | 83 (64.3) |
T3 | 43 (9.0) | 2 (2.4) | NA | 2 (1.6) |
T4 | 18 (3.8) | 0 (0) | NA | 0 (0) |
TX | 3 (0.6) | 0 (0) | NA | 0 (0) |
N | ||||
N0 | 307 (64.4) | 80 (96.4) | NA | 95 (73.6) |
N1 | 90 (18.9) | 3 (3.6) | NA | 34 (26.4) |
N2 | 67 (14.0) | 0 (0) | NA | 0 (0) |
NX | 2 (0.4) | 0 (0) | NA | 0 (0) |
Unknow | 1 (0.2) | 0 (0) | NA | 0 (0) |
M | ||||
M0 | 313 (65.6) | 83 (100) | NA | 129 (100) |
M1 | 24 (5.0) | 0 (0) | NA | 0 (0) |
MX | 136 (28.5) | 0 (0) | NA | 0 (0) |