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Fig. 1 | Respiratory Research

Fig. 1

From: Roles of airway basal stem cells in lung homeostasis and regenerative medicine

Fig. 1

The lung endoderm. During lung development, the lung endoderm is specified from the ventral anterior foregut endoderm, and the early endoderm progenitors committed to lung epithelial lineages are marked by NK2 homeobox 1 (NKX2− 1). Following the esophagus and lung split, these endodermal progenitors (NKX2.1 +) then quickly undergo specification for either the proximal conducting airway epithelium (SOX2 +) or the peripheral distal airway epithelium (SOX9 + and ID2 +)

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