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Table 1 Mutation burden analysis of 6 genes identified in previous GWAS studies

From: Burden of rare coding variants reveals genetic heterogeneity between obese and non-obese asthma patients in the African American population

Gene ID

P value (asthma vs controls)

P value (obesity asthma vs controls)

P value (non-obese asthma vs controls)

P value (obese asthma vs non-obese asthma)

P value (non-obese asthma vs obese asthma)

P value (obesity)*

SLC9A4

0.005

0.088

1.03E−03

0.976

0.056

0.273

TSLP

1.43E−03

0.027

5.50E−04

0.964

0.123

0.149

PSMB8

0.005

0.013

0.024

0.629

0.549

0.577

GPR182

0.010

0.013

0.061

0.519

0.711

0.687

IGSF5

0.007

1.89E-03

0.298

0.074

0.970

0.420

IKZF4

0.009

9.40E-04

0.643

0.015

0.997

0.017

RSPH3

7.87E−03

0.168

3.40E−04

0.993

0.009

0.010

  1. *Logistic regression adjusted for asthma