LABA/LAMA FDC (N = 340) | Triple therapy (N = 784) | |
---|---|---|
Sex, n (%) | ||
Male | 172 (50.6) | 477 (60.8) |
Female | 168 (49.4) | 307 (39.2) |
Age (years), mean (SD) | 69.9 (9.9) | 68.8 (9.2) |
Age groups, n (%) | ||
< 65 years | 100 (29.4) | 258 (32.9) |
65–75 years | 129 (37.9) | 312 (39.8) |
> 75 years | 111 (32.6) | 214 (27.3) |
Body-mass index (kg/m2), mean (SD) | 27.8 (5.8) | 27.2 (5.5) |
Duration since primary diagnosis (years), mean (SD) | 6.7 (4.7) | 8.0 (5.6) |
Duration since primary diagnosis, n (%) | ||
≤ 1 year | 26 (7.6) | 43 (5.5) |
> 1 year | 305 (89.7) | 707 (90.2) |
Missing values | 9 (2.6) | 34 (4.3) |
Symptoms of COPD*, n (%) | ||
None | 0 (0.0) | 0 (0.0) |
Exertional dyspnoea | 314 (92.4) | 747 (95.3) |
Dyspnoea at rest | 90 (26.5) | 194 (24.7) |
Chest tightness/chest pain | 150 (44.1) | 327 (41.7) |
Cough | 291 (85.6) | 653 (83.3) |
Wheezing or grunting | 104 (30.6) | 266 (33.9) |
Prolonged expiration | 123 (36.2) | 251 (32.0) |
Restricted exercise tolerance | 265 (77.9) | 653 (83.3) |
Missing values | 4 (1.2) | 7 (0.9) |
FEV1 (litres), mean (SD) | 1.7 (0.7) | 1.5 (0.6) |
FEV1 predicted, mean (SD) | 66.9 (24.7) | 57.7 (22.8) |
Smoking status, n (%) | ||
Smoker | 115 (33.8) | 235 (30.0) |
Ex-smoker | 168 (49.4) | 435 (55.5) |
Non-smoker | 57 (16.8) | 114 (14.5) |
Years smoking†, mean (SD) | 34.4 (10.1) | 35.2 (11.8) |
Pack-years†, mean (SD) | 35.2 (18.8) | 36.1 (22.0) |