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Fig. 6 | Respiratory Research

Fig. 6

From: Transcriptional inhibition of miR-486-3p by BCL6 upregulates Snail and induces epithelial–mesenchymal transition during radiation-induced pulmonary fibrosis

Fig. 6

BCL6 promote EMT by repress miR-486-3p expression following IR. A Overexpression of BCL6 in two types of cells to check the changes of EMT-related proteins. B Knockdown of BCL6 after irradiation and observation of EMT and target protein expression in two cell types. C Firstly, BCL6 was overexpressed in cells and then transfected with miR-486-3p mimic to check the related proteins change. D Overexpression of BCL6 in cells and then knockdown of the target gene Snail, observation of changes in EMT-related proteins. On the right, the protein gray value analysis was showed. *p < 0.05 compared with NC; #p < 0.05 compared with OE-BCL6

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Respiratory Research

ISSN: 1465-993X

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