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Fig. 5 | Respiratory Research

Fig. 5

From: Transcriptional inhibition of miR-486-3p by BCL6 upregulates Snail and induces epithelial–mesenchymal transition during radiation-induced pulmonary fibrosis

Fig. 5

IR actives BCL6 which regulates miR-486-3p transcription. A Detection of pri-miR-486-3p expression at different time after irradiation of both cells using qRT-PCR. B Detection of BCL6 mRNA expression at different time after irradiation using qRT-PCR. C Changes of transcription factor BCL6 protein levels at different time after irradiation. D, E Changes of pri-miR-486-3p and miR-486-3p after overexpress BCL6 in both cells. F Schematic diagram of the binding site of BCL6 and miR-486-3p promoter region. G Dual luciferase reporter system validates the binding site. *p < 0.05

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Respiratory Research

ISSN: 1465-993X

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