Skip to main content

Table 4 Statistical Analysis of Variables Correlated with the Occurrence of complications

From: Bilateral versus unilateral balloon pulmonary angioplasty for inoperable chronic thromboembolic pulmonary hypertension

 

Univariate analysis

Multivariate analysis

Odds Ratio

95% CI

p value

Odds Ratio

95% CI

p value

Age (years)

0.998

0.958–1.040

0.928

–

–

–

Sex (female)

0.943

0.359–2.481

0.906

–

–

–

Bilateral

1.201

0.475–3.035

0.699

–

–

–

First session

1.160

0.523–2.572

0.715

–

–

–

WHO functional class (III-IV versus I-II)

3.981

1.540–10.290

0.004

3.268

1.216–8.781

0.019

Period of BPA procedure (recent versus initial period#)

0.613

0.240–1.567

0.307

–

–

–

Mean PAP (mmHg)

1.046

1.004–1.090

0.030

–

–

–

PVR (Wood Unit)

1.109

1.029–1.195

0.007

1.085

1.004–1.172

0.040

Cardiac index (L/min/m2)

0.543

0.291–1.014

0.055

–

–

–

Vessels treated/session

1.126

0.977–1.297

0.102

–

–

–

Lobes treated/session

1.573

1.019–2.427

0.041

–

–

–

Lesions treated/session

1.026

0.910–1.155

0.677

–

–

–

Complex lesions treated/session

0.732

0.469–1.141

0.168

–

–

–

Largest balloon size used/session (mm)

0.654

0.428–1.001

0.050

–

–

–

NT-proBNP (pg/ml)

1.000246

1.000052–1.000440

0.013

–

–

–

The amount of contrast media given (ml)

1.000

0.993–1.007

0.949

–

–

–

Dose area product (μGy m2)

0.999919

0.999736–1.000102

0.385

–

–

–

Operation duration

1.005

0.998–1.013

0.144

–

–

–

  1. Multivariate analysis was made using variables with significant correlation of p < 0.01 in univariate analysis
  2. CI confidence intervals, PAP pulmonary artery pressure, PVR pulmonary vascular resistance, NT-proBNP N-terminal pro-B-type natriuretic peptide, WHO World Health Organization
  3. *Complex lesions were defined as subtotal occlusions and total occlusions. #Initial period was defined by the initial 105 BPA sessions (50%) performed between January 2019 and June 2020. The recent period was defined by the recent 105 BPA sessions (50%) performed between July 2020 and November 2021