Bilateral versus unilateral balloon pulmonary angioplasty for inoperable chronic thromboembolic pulmonary hypertension

Table 4 Statistical Analysis of Variables Correlated with the Occurrence of complications

	Univariate analysis			Multivariate analysis
	Odds Ratio	95% CI	p value	Odds Ratio	95% CI	p value
Age (years)	0.998	0.958–1.040	0.928	–	–	–
Sex (female)	0.943	0.359–2.481	0.906	–	–	–
Bilateral	1.201	0.475–3.035	0.699	–	–	–
First session	1.160	0.523–2.572	0.715	–	–	–
WHO functional class (III-IV versus I-II)	3.981	1.540–10.290	0.004	3.268	1.216–8.781	0.019
Period of BPA procedure (recent versus initial period#)	0.613	0.240–1.567	0.307	–	–	–
Mean PAP (mmHg)	1.046	1.004–1.090	0.030	–	–	–
PVR (Wood Unit)	1.109	1.029–1.195	0.007	1.085	1.004–1.172	0.040
Cardiac index (L/min/m²)	0.543	0.291–1.014	0.055	–	–	–
Vessels treated/session	1.126	0.977–1.297	0.102	–	–	–
Lobes treated/session	1.573	1.019–2.427	0.041	–	–	–
Lesions treated/session	1.026	0.910–1.155	0.677	–	–	–
Complex lesions treated/session	0.732	0.469–1.141	0.168	–	–	–
Largest balloon size used/session (mm)	0.654	0.428–1.001	0.050	–	–	–
NT-proBNP (pg/ml)	1.000246	1.000052–1.000440	0.013	–	–	–
The amount of contrast media given (ml)	1.000	0.993–1.007	0.949	–	–	–
Dose area product (μGy m2)	0.999919	0.999736–1.000102	0.385	–	–	–
Operation duration	1.005	0.998–1.013	0.144	–	–	–

Multivariate analysis was made using variables with significant correlation of p < 0.01 in univariate analysis
CI confidence intervals, PAP pulmonary artery pressure, PVR pulmonary vascular resistance, NT-proBNP N-terminal pro-B-type natriuretic peptide, WHO World Health Organization
*Complex lesions were defined as subtotal occlusions and total occlusions. #Initial period was defined by the initial 105 BPA sessions (50%) performed between January 2019 and June 2020. The recent period was defined by the recent 105 BPA sessions (50%) performed between July 2020 and November 2021

ISSN: 1465-993X