Skip to main content

Table 3 IPF GWAS [4] genes in the overlapping differentially expressed gene groups

From: Lung tissue shows divergent gene expression between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

Gene IPF vs. control log2FC Unadjusted p value Adjusted p value Overlap group
AKAP13 −0.25 3.48E−21 1.88E−20 3
DEPTOR 0.33 2.13E−06 4.07E−06 1
DPP9 0.08 1.43E−05 2.56E−05 1
  1. The gene nearest to each lead GWAS single nucleotide polymorphism is included
  2. IPF vs. control log2FC and Benjamini–Hochberg adjusted p value shown. Group 1: genes with increased expression in IPF and COPD; Group 2: genes with increased expression in IPF but decreased expression in COPD; Group 3: genes with decreased expression in IPF but increased expression in COPD; Group 4: genes with decreased expression in IPF and COPD
  3. IPF idiopathic pulmonary fibrosis, GWAS genome-wide association study, log2FC log2 fold change