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Table 3 IPF GWAS [4] genes in the overlapping differentially expressed gene groups

From: Lung tissue shows divergent gene expression between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

Gene

IPF vs. control log2FC

Unadjusted p value

Adjusted p value

Overlap group

AKAP13

−0.25

3.48E−21

1.88E−20

3

DEPTOR

0.33

2.13E−06

4.07E−06

1

DPP9

0.08

1.43E−05

2.56E−05

1

  1. The gene nearest to each lead GWAS single nucleotide polymorphism is included
  2. IPF vs. control log2FC and Benjamini–Hochberg adjusted p value shown. Group 1: genes with increased expression in IPF and COPD; Group 2: genes with increased expression in IPF but decreased expression in COPD; Group 3: genes with decreased expression in IPF but increased expression in COPD; Group 4: genes with decreased expression in IPF and COPD
  3. IPF idiopathic pulmonary fibrosis, GWAS genome-wide association study, log2FC log2 fold change