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Table 1 LTRC subject characteristics

From: Lung tissue shows divergent gene expression between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

Characteristic IPF COPD Control p value
IPF vs. control
p value
COPD vs. control
n 231 377 267   
Age, years 63.39 (7.90) 63.78 (9.05) 61.90 (12.65) 0.123 0.029
Male sex 157 (68.0) 201 (53.3) 105 (39.3) < 0.001 0.001
Race     0.180 0.222
White 205 (88.7) 344 (91.2) 246 (92.1)   
Asian 3 (1.3) 0 (0) 0 (0)   
Black 10 (4.3) 26 (6.9) 11 (4.1)   
Hispanic 7 (3.0) 5 (1.3) 8 (3.0)   
Other race 6 (2.6) 2 (0.5) 2 (0.7)   
BMI, kg/m2 29.72 (5.44) 26.03 (5.11) 28.75 (5.88) 0.060 < 0.001
Current smoking 3 (1.3) 25 (6.6) 10 (3.7) 0.154 0.157
Ever smoking 152 (65.8) 365 (96.8) 173 (64.8) 0.888 < 0.001
Smoking pack-years 18.06 (23.33) 47.76 (30.48) 19.11 (26.75) 0.642 < 0.001
Pre-bronchodilator FEV1, % predicted 66.17 (19.28) 40.18 (19.74) 96.62 (12.83) < 0.001 < 0.001
Pre-bronchodilator FVC, % predicted 61.11 (18.06) 67.94 (18.11) 96.67 (13.10) < 0.001 < 0.001
Pre-bronchodilator FEV1/FVC 0.83 (0.08) 0.43 (0.15) 0.77 (0.06) < 0.001 < 0.001
DLCO, % predicted 38.95 (19.80) 40.98 (18.22) 73.78 (15.52) < 0.001 < 0.001
  1. Data presented as mean (SD) or no. (%)
  2. LTRC Lung Tissue Research Consortium, IPF idiopathic pulmonary fibrosis, COPD chronic obstructive pulmonary disease, BMI body mass index, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, DLCO diffusion capacity for carbon monoxide