Table 1 LTRC subject characteristics
| Characteristic | IPF | COPD | Control |
p value IPF vs. control |
p value COPD vs. control |
|---|---|---|---|---|---|
| n | 231 | 377 | 267 | ||
| Age, years | 63.39 (7.90) | 63.78 (9.05) | 61.90 (12.65) | 0.123 | 0.029 |
| Male sex | 157 (68.0) | 201 (53.3) | 105 (39.3) | < 0.001 | 0.001 |
| Race | 0.180 | 0.222 | |||
| White | 205 (88.7) | 344 (91.2) | 246 (92.1) | ||
| Asian | 3 (1.3) | 0 (0) | 0 (0) | ||
| Black | 10 (4.3) | 26 (6.9) | 11 (4.1) | ||
| Hispanic | 7 (3.0) | 5 (1.3) | 8 (3.0) | ||
| Other race | 6 (2.6) | 2 (0.5) | 2 (0.7) | ||
| BMI, kg/m2 | 29.72 (5.44) | 26.03 (5.11) | 28.75 (5.88) | 0.060 | < 0.001 |
| Current smoking | 3 (1.3) | 25 (6.6) | 10 (3.7) | 0.154 | 0.157 |
| Ever smoking | 152 (65.8) | 365 (96.8) | 173 (64.8) | 0.888 | < 0.001 |
| Smoking pack-years | 18.06 (23.33) | 47.76 (30.48) | 19.11 (26.75) | 0.642 | < 0.001 |
| Pre-bronchodilator FEV1, % predicted | 66.17 (19.28) | 40.18 (19.74) | 96.62 (12.83) | < 0.001 | < 0.001 |
| Pre-bronchodilator FVC, % predicted | 61.11 (18.06) | 67.94 (18.11) | 96.67 (13.10) | < 0.001 | < 0.001 |
| Pre-bronchodilator FEV1/FVC | 0.83 (0.08) | 0.43 (0.15) | 0.77 (0.06) | < 0.001 | < 0.001 |
| DLCO, % predicted | 38.95 (19.80) | 40.98 (18.22) | 73.78 (15.52) | < 0.001 | < 0.001 |