Exploring genetic association of insomnia with allergic disease and asthma: a bidirectional Mendelian randomization study

Table 2 Pleiotropy and heterogeneity test of allergic disease, asthma and its phenotype on insomnia

Exposures	MR-Egger test			Cochrane Q test								MR-PRESSO global test
	MR-Egger test			MR-Egger				IVW				MR-PRESSO global test
	Intercept	SE	P-value	Q	Q_df	I²	P-value	Q	Q_df	I²	P-value	RSSobs	P-value
Allergic disease	− 0.001	0.002	0.675	116.3	96	0.175	0.077	116.6	97	0.168	0.086	118.622	0.101
Asthma	0.0002	0.002	0.887	101.4	84	0.172	0.095	101.4	85	0.162	0.108	103.520	0.118
Moderate-severe asthma	− 0.004	0.010	0.674	11.4	10	0.140	0.325	11.6	11	0.055	0.391	13.901	0.380

ISSN: 1465-993X