Fig. 2

Scatterplots of potential effects of SNPs on insomnia versus allergic disease, asthma, and its phenotypes. A Allergic disease; B asthma; C moderate–severe asthma; D adult-onset asthma; E childhood asthma. Analyses were conducted using the fixed and multiplicative random effects IVW, MR-Egger, Weighted median methods. The slope of each line corresponding to the estimated MR effect per method