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Table 2 Distribution of allergens in different age groups and sex

From: Allergens sensitization among children with allergic diseases in Shanghai, China: age and sex difference

Allergens

Age group [n (%)]

p

Sex [n (%)]

p

0–1 years

(n = 2373)

 > 1–3 years

(n = 5517)

 > 3–6 years

(n = 17,689)

 > 6–12 years

(n = 12,893)

 > 12–18 years

(n = 1454)

Total

(N = 39,926)

Male

(n = 24,057)

Female

(n = 15,869)

Dust mite

34 (1.4)a

242 (4.4)b

2758 (15.6)c

3321 (25.8)d

461 (31.7)e

6816 (17.1)

 < 0.001#

4391 (18.3)

2425 (15.3)

 < 0.001#

House mite

55 (2.3)a

679 (12.3)b

6320 (35.7)c

6175 (47.9)d

778 (53.5)e

14,007 (35.1)

 < 0.001#

8926 (37.1)

5081 (32.0)

 < 0.001#

Cat epithelium

200 (8.4)a,b,c

536 (9.7)c,d

1369 (7.7)b

1149 (8.9)a,c

165 (11.3)d

3419 (8.6)

 < 0.001#

2210 (9.2)

1209 (7.6)

 < 0.001#

Dog epithelium

71 (3.0)a

303 (5.5)b

1144 (6.5)b

812 (6.3)b

102 (7.0)b

2432 (6.1)

 < 0.001#

1596 (6.6)

836 (5.3)

0.001#

Cockroach

25 (1.1)a

77 (1.4)a

363 (2.1)b

279 (2.2)b

29 (2.0)a,b

773 (1.9)

 < 0.001#

489 (2.0)

284 (1.8)

0.09

Mold

31 (1.3)a

273 (4.9)b

2357 (13.3)c

2502 (19.4)d

316 (21.7)d

5479 (13.7)

 < 0.001#

3404 (14.1)

2075 (13.1)

0.002#

Grass

14 (0.6)a

42 (0.8)a

209 (1.2)a

206 (1.6)b

35 (2.4)b

506 (1.3)

 < 0.001#

339 (1.4)

167 (1.1)

0.002#

Trees

70 (2.9)a

230 (4.2)a,b

874 (4.9)b

573 (4.4)b

64 (4.4)a,b

1811 (4.5)

 < 0.001#

1119 (4.7)

692 (4.4)

0.17

Mulberry

10 (0.4)a

47 (0.9)a,b

202 (1.1)b

164 (1.3)b

24 (1.7)b

447 (1.1)

 < 0.001#

304 (1.3)

143 (0.9)

0.001#

Amaranth

17 (0.7)a

69 (1.3)a,b

224 (1.3)a,b

148 (1.1)a,b

25 (1.7)b

483 (1.2)

0.06

320 (1.3)

163 (1.0)

0.007

Aeroallergen

417 (17.6)a

1719 (31.2)b

9375 (53.0)c

8230 (63.8)d

980 (67.4)d

20,721 (51.9)

 < 0.001#

13,022 (54.1)

7699 (48.5)

 < 0.001#

Milk

424 (17.9)a,b

1164 (21.1)c

3337 (18.9)b

2092 (16.2)a,d

206 (14.2)d

7223 (18.1)

 < 0.001#

4541 (18.9)

2682 (16.9)

 < 0.001#

Beef

7 (0.3)a

64 (1.2)b

344 (1.9)c

238 (1.8)c

22 (1.5)b,c

675 (1.7)

 < 0.001#

419 (1.7)

256 (1.6)

0.33

Nut

157 (6.6)a,b

654 (11.9)c

1854 (10.5)d

870 (6.7)b

68 (4.7)a

3603 (9.0)

 < 0.001#

2278 (9.5)

1325 (8.3)

 < 0.001#

Egg

474 (20.0)a

1169 (21.2)a

3725 (21.1)a

1639 (12.7)b

106 (7.3)c

7113 (17.8)

 < 0.001#

4211 (17.5)

2902 (18.3)

0.045

Crab

75 (3.2)a

488 (8.8)b

1252 (7.1)c

451 (3.5)a

44 (3.0)a

2310 (5.8)

 < 0.001#

1492 (6.2)

818 (5.2)

 < 0.001#

Shrimp

57 (2.4)a

348 (6.3)b

949 (5.4)b

369 (2.9)a

42 (2.9)a

1765 (4.4)

 < 0.001#

1149 (4.8)

616 (3.9)

 < 0.001#

Mango

22 (0.9)a,b

36 (0.7)a,b

151 (0.9)b

69 (0.5)a

10 (0.7)a,b

288 (0.7)

0.015

192 (0.8)

96 (0.6)

0.026

Food allergen

872 (36.7)a

2227 (40.4)b

6486 (36.7)a

3630 (28.2)c

343 (23.6)d

13,558 (34.0)

 < 0.001#

8371 (34.8)

5187 (32.7)

 < 0.001#

Overall allergen

1062 (44.8)a

2996 (54.3)b

11,626 (65.7)c

9037 (70.1)d

1036 (71.3)d

25,757 (64.5)

 < 0.001#

15,937 (66.2)

9820 (61.9)

 < 0.001#

  1. Bolding indicates p < 0.05
  2. # indicates if below Bonferroni-adjusted p < 0.0025 (0.05/20 outcomes)
  3. For the comparison of each allergen, significant differences between two age groups (p < 0.05)are indicated with different letters (a–e)