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Table 2 Mean concentrations of DPPC, POPG, and B-YL in Bronchoalveolar Lavage samples from rabbits treated with B-YL:Trehalose or B-YL:Lactose

From: Efficacy, dose–response, and aerosol delivery of dry powder synthetic lung surfactant treatment in surfactant-deficient rabbits and premature lambs

Dose (mg/kg)

DPPC (µg/mL)

POPG (µg/mL)

B-YL (µg/mL)

DPPC:POPG

30

173 ± 66

31.3 ± 9.1

6.85 ± 1.7

5.5:1 (16:3)

60

332 ± 31

71.0 ± 48

7.70 ± 4.7

4.7:1 (15:3)

120

590 ± 114

238 ± 79

14.1 ± 2.3

2.5:1 (7:3)

240

665 ± 121

278 ± 98

21.9 ± 4.5

2.4:1 (7:3)

  1. Data are represented as mean ± SEM, n = 6–15 per group
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Respiratory Research

ISSN: 1465-993X

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