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Table 2 Mean concentrations of DPPC, POPG, and B-YL in Bronchoalveolar Lavage samples from rabbits treated with B-YL:Trehalose or B-YL:Lactose

From: Efficacy, dose–response, and aerosol delivery of dry powder synthetic lung surfactant treatment in surfactant-deficient rabbits and premature lambs

Dose (mg/kg) DPPC (µg/mL) POPG (µg/mL) B-YL (µg/mL) DPPC:POPG
30 173 ± 66 31.3 ± 9.1 6.85 ± 1.7 5.5:1 (16:3)
60 332 ± 31 71.0 ± 48 7.70 ± 4.7 4.7:1 (15:3)
120 590 ± 114 238 ± 79 14.1 ± 2.3 2.5:1 (7:3)
240 665 ± 121 278 ± 98 21.9 ± 4.5 2.4:1 (7:3)
  1. Data are represented as mean ± SEM, n = 6–15 per group