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Fig. 3 | Respiratory Research

Fig. 3

From: Efficacy, dose–response, and aerosol delivery of dry powder synthetic lung surfactant treatment in surfactant-deficient rabbits and premature lambs

Fig. 3

Phospholipid (DPPC and POPG) and B-YL concentrations (mean ± SEM) in lung tissue (µg/g) from surfactant-deficient rabbits measured 2 h after intratracheal insufflation of dry powder. A Lung DPPC and POPG concentrations after aerosol delivery of DP B-YL:Lactose surfactant. B Lung DPPC and POPG concentrations after DP B-YL:Trehalose surfactant treatment. C B-YL peptide concentration in lung tissue after B-YL:Lactose and B-YL:Trehalose surfactant treatment. *p = 0.0285 for B-YL 30 vs 120 mg/kg; **p = 0.0348 for DPPC 30 vs 120 mg/kg; ▲p = 0.0385 for POPG 30 vs 120 mg/kg; #p = 0.0080 for DPPC + POPG 30 vs 120 mg/kg. Lower limit of quantitation (LLOQ) was 0.1 µg/mL for DPPC and POPG and 50 ng/mL for B-YL

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Respiratory Research

ISSN: 1465-993X

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