Fig. 4

AT2 damage and repair induced by PM2.5 exposure may be related to the down-regulation of cell differentiation genes. A Visualization of differentially expressed genes in alveolar maintaining phase. The red dots represent up-regulated differentially expressed genes, the blue dots represent down-regulated differentially expression genes and the grey dots represent genes with no significant change. B Pathway analysis of down-regulated genes in alveolar maintaining phase. C GO analysis of down-regulated genes in alveolar maintaining phase. D Visualization of differentially expressed genes in alveolar differentiation phase. The red dots represent up-regulated differentially expressed genes, the blue dots represent down-regulated differentially expression genes and the grey dots represent genes with no significant change. E Pathway analysis of down-regulated genes in alveolar differentiation phase. F GO analysis of down-regulated genes in alveolar differentiation phase