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Table 2 Lung function and cardiopulmonary exercise variables of transthyretin cardiac amyloidosis patients (n = 20)

From: Pulmonary 99mTc-HMDP uptake correlates with restrictive ventilatory defects and abnormal lung reactance in transthyretin cardiac amyloidosis patients

  

n (%) of patients with value < 75% predicted

FEV1, liter

1.9 ± 0.6

 

FEV1, % predicted

66.0 ± 21.0

14 (70)

FVC, liter

2.4 ± 0.7

 

FVC, % predicted

69.0 ± 16.0

14 (70)

FEV1/FVC, %

75.0 ± 9.0

1 (5)

TLC, liter

5.0 ± 1.1

 

TLC, % predicted

68.0 ± 17.0

14 (70)

Rrs(5), kPa L−1 s−1

0.4 ± 0.1

 

Xrs(5), kPa L−1 s−1

− 0.1 ± 0.1

 

DLCO (%)n=11

71.0 ± 17.0

6 (55)

KCO (%)n=11

100.0 ± 16.0

0 (0)

Peak VO2, mL kg−1 min−1 n=13

15.0 ± 2.4

 

Predicted VO2, % n=13

65.0 ± 19.0

11 (85)

Peak RER n=13

1.2 ± 0.1

 

Ventilatory reserve, % n=13

32.0 ± 19.0

5 (38)

Peak O2 pulse, % n=13

75.0 ± 16.0

6 (46)

Peak systolic pressure, mmHg n=13

175.0 ± 32.0

 

Peak heart rate, % maximal predictedn=13

83.0 ± 14.0

 
  1. Results are presented as mean ± standard deviation and as absolute number and percent (n (%)). (n) indicates sample size when different from 20
  2. FEV1 forced expiratory volume in 1 s; FVC forced vital capacity; TLC total lung capacity; Rrs(5) respiratory system resistance at 5 Hz; Xrs(5) respiratory system reactance at 5 Hz; DLCO diffusion capacity of the lung for carbon monoxide; KCO transfer coefficient of the lung for carbon monoxide; VO2 oxygen uptake; RER respiratory exchange ratio
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Respiratory Research

ISSN: 1465-993X

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