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Fig. 5 | Respiratory Research

Fig. 5

From: LPA1 antagonist BMS-986020 changes collagen dynamics and exerts antifibrotic effects in vitro and in patients with idiopathic pulmonary fibrosis

Fig. 5

Effects of BMS-986020 on LPA- or TGF-β1–stimulated fibrogenesis in the Scar-in-a-Jar in vitro model. Shown are ECM-neoepitope biomarkers over time for untreated, vehicle-, and BMS-986020–treated fibroblasts. Similar results were obtained in a prior experiment. ECM extracellular matrix; LPA lysophosphatidic acid; SEM standard error of the mean; Stim stimulation; TGF-β1 transforming growth factor-beta 1. ECM-neoepitope biomarker abbreviations are defined in Table 1

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