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Table 1 Patient’s characteristics and comparison of clinical factors between patients with a normal and reduced exercise capacity

From: Identification of factors impairing exercise capacity after severe COVID-19 pulmonary infection: a 3-month follow-up of prospective COVulnerability cohort

Parameters

All patients

(n = 105)

Normal exercise capacity

(n = 68)

Reduced exercise capacity

(n = 37)

p-Value

Age, years

59.21 ± 11.81

59.68 ± 12.16

58.35 ± 11.26

0.585

Male (%)

79 (75.2)

46 (67.6)

33 (89.2)

0.015

BMI before COVID-19, kg/m2

29.11 ± 5.51

30.29 ± 5.64

27.16 ± 4.74

0.009

BMI, kg/m2

27.92 ± 4.98

29.07 ± 5.24

25.79 ± 3.68

0.001

Change in BMI before-after COVID-19, kg/m2

− 1.16 ± 1.93

− 0.90 ± 1.59

− 1.59 ± 2.35

0.105

Tobacco history (%)

48 (45.7)

34 (50)

14 (37.8)

0.232

Smoking, pack-years

11.69 ± 16.29

11.5 ± 15.22

12.06 ± 18.38

0.874

mMRC dyspnea scale (0/ 1/ 2/ 3/ 4)

67/ 31/ 5/ 2/ 0

46/ 21/ 1/ 0/ 0

24/ 12/ 1/ 0/ 0

0.61

Comorbidities

    

Hypertension (%)

44 (41.9)

25 (36.8)

19 (51.4)

0.148

Diabetes (%)

29 (27.6)

12 (17.6)

17 (45.9)

0.002

Dyslipidemia (%)

21 (20)

13 (19.1)

8 (21.6)

0.759

Ischemic cardiomyopathy (%)

17 (16.2)

12 (17.6)

5 (13.5)

0.583

Obstructive sleep apnea (%)

15 (14.3)

8 (11.8)

7 (18.9)

0.317

Malignancy (%)

14 (13.5)

8 (11.9)

6 (16.2)

0.541

Chronic kidney disease (%)

11 (10.5)

3 (4.4)

8 (21.6)

0.006

COPD (%)

1 (1)

1 (1.5)

0 (0)

0.459

During COVID-19 hospitalisation

    

ICU stay (%)

45 (43.3)

26 (38.8)

19 (51.4)

0.216

HFNC (%)

16 (15.7)

10 (15.2)

6 (16.7)

0.841

IMV (%)

26 (25.2)

14 (21.2)

12 (32.4)

0.209

Tracheotomy (%)

2 (1.9)

1 (1.5)

1 (2.7)

0.675

ECMO (%)

4 (3.9)

1 (1.5)

3 (8.1)

0.097

Pulmonary embolism (%)

8 (7.8)

7 (10.6)

1 (2.7)

0.150

Acute kidney injury (%)

23 (22.1)

11 (16.2)

12 (33.3)

0.045

Cardiogenic shock (%)

2 (1.9)

2 (3)

0 (0)

0.289

  1. Data are presented as n, n (%) or mean ± SD. Bold type represents statistical significance. BMI Body mass index, mMRC modified Medical Research Council, COPD chronic obstructive pulmonary disease, ICU intensive care unit, IMV invasive mechanical ventilation, HFNC high-flow nasal cannula, ECMO extracorporeal membrane oxygenation