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Table 4 Binary logistic regression analysis of univariate analysis and multivariate analysis with dyspnea of CTD-ILD patient

From: Quantitative evaluation of disease severity in connective tissue disease-associated interstitial lung disease by dual-energy computed tomography

 

Univariate Analysis

Multivariate Analysis

 

β value

SE

Wals

OR (95%CI)

P

β value

SE

Wals

OR (95%CI)

P

Age (y)

− 0.020

0.018

1.328

0.980 (0.946–1.014)

.249

− 0.042

0.020

4.522

0.959 (0.923–0.997)

.033

Gender (male/female)

1.417

0.669

4.488

4.125 (1.112–15.304)

.034

     

Han nationality

0.093

0.630

0.022

1.097 (0.319–3.770)

.883

     

BMI (kg/m2)

0.063

0.051

1.516

1.065 (0.963–1.179)

.218

     

Former/current smoke

− 0.875

0.561

2.436

0.417 (0.139–1.251)

.119

     

Comorbidity

0.063

0.338

0.035

1.065 (0.549–2.065)

.852

     

Lung volume (L)

− 0.461

0.188

5.982

0.631 (0.436–0.913)

.014

     

Average Zeff value

1.096

0.325

11.379

2.991 (1.583–5.653)

.001

1.293

.347

13.895

3.644 (1.846–7.192)

.000

Average MCTN (HU)

0.011

0.003

10.888

1.012 (1.005–1.018)

.001

     

Type of CTD

  

2.398

 

.302

     

 SCTD vs UCTD

0.507

0.428

1.398

1.660 (0.717–3.843)

.237

     

 MCTD vs UCTD

0.952

0.649

2.151

2.591 (0.726–9.246)

.142

     
  1. Total, No. = 145, significance with p < 0.05
  2. CTD-ILD connective tissue disease associated interstitial lung disease, BMI body mass index, MCTN monochromatic CT number at 70 keV, CTD connective tissue disease, SCTD specific connective tissue disease, UCTD undifferentiated connective tissue disease, MCTD mixed connective tissue disease