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Table 1 Connective tissue disease associated interstitial lung disease (CTD-ILD) cohort demographic and clinical characteristics

From: Quantitative evaluation of disease severity in connective tissue disease-associated interstitial lung disease by dual-energy computed tomography

Demographic and clinical characteristics

Mean ± SD or N (%) or Median (range)

Age (year)

50.10 ± 9.64

Female, No. (%)

132 (89.8)

BMI (kg/m2) §

23.10 ± 3.29

Ethnicity (Han nationality), No. (%)

136 (92.5)

Former/current smoker, No. (%)

17 (11.6)

Comorbidity, No. (%)

87 (59.2)

Type of CTD

 

 Specific CTD (SCTD)

102 (69.4)

  Systemic sclerosis/scleroderma (SSc)

33 (22.4)

  Polymyositis/dermatomyositis (PM/DM)

39 (26.5)

  Sjögren Syndrome (SjS)

10 (6.8)

  Rheumatoid Arthritis (RA)

11 (7.5)

  Systemic lupus erythematosus (SLE)

9 (6.1)

 Undifferentiated CTD (UCTD)

30 (20.4)

 Mixed CTD (MCTD)

15 (10.2)

Dyspnea (Borg dyspnea score)

 

 No dyspnea

76 (51.7)

 Mild dyspnea

53 (36.1)

 Moderate to Severe dyspnea

16 (10.9)

 NA

2 (1.4)

Cough (LCQ)

 

 No cough

81 (55.1)

 Mild cough

39 (26.5)

 Severe cough

25 (17.0)

 NA

2 (1.4)

Pulmonary Function Test ¶

 

 FVC% predicted ¶

89.59 ± 22.94

 FEV1%predicted ¶

87.50 ± 21.14

 TLC%predicted ¶

85.80 ± 19.40

 DLCO% predicted+

74.55 (58.13, 84.48)

Severity of CTD-ILD

 

 Limited CTD-ILD

89 (60.5)

 Extensive CTD-ILD

39 (26.5)

 NA

19 (13.0)

SF-36 λ (range 0–100)

 

 Physical component summary (PCS) score

51.80 (45.28, 56.99)

 Mental component summary (MCS) score

52.33 (43.97, 57.53)

  1. Data are presented as mean ± SD or n (%) or Median (range)
  2. Total-No. = 147, unless otherwise stated; §: N = 146; λ: N = 145; ¶: N = 114; + : N = 112
  3. BMI body mass index, CTD connective tissue disease, ILD interstitial lung disease, LCQ Leicester cough questionnaire, FVC forced vital capacity, FEV1 forced expiratory volume in one second, TLC total lung capacity, DLCO diffusion capacity of the lung for carbon monoxide, SF-36 36 item short form health survey, NA not available