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Table 3 Granulomatous organ involvement

From: Infliximab therapy in refractory sarcoidosis: a multicenter real-world analysis

 

Number of patient (%)

Organ involvement

 

 Lung

30 (91)

 Skin

15 (45)

  Lupus pernio

8

  Other skin manifestation

7

 Upper airway

9 (27)

 Eye

7 (21)

 Liver

4 (12)

 CNS

6 (18)

 Cardiac

3 (9)

 GI

1 (3)

 Spleen

3 (9)

 Peripheral lymph node

2 (6)

 Bone marrow

1 (3)

 Muscle

1 (3)

 Arthritis

1 (3)

Organ involvement

 1

12 (36)

 2

7 (21)

 ≥ 3

14 (43)

 Multiorgan (≥ 2)

21 (64)

Organ/manifestation for which infliximab was initiated

 

 Lungs

14 (33)

 Skin

12 (28)

 Upper airway

7 (16)

 CNS

6 (14)

 Peripheral lymph node

1 (2)

 GI

1 (2)

 Uveitis

1 (2)

 Arthritis

1 (2)

Concomitant therapy

 

 Corticosteroid alone

5 (15)

 Second line immunosuppressive alone

9 (27)

 Corticosteroid + second line immunosuppressive

19 (58)

  1. GI gastrointestinal; CNS central nervous system