From: Plasma proteome changes linked to late phase response after inhaled allergen challenge in asthmatics
All (n = 32) | Single responders (n = 18) | Dual responders (n = 14) | |
---|---|---|---|
Sex (F/M) | 16/16 | 9/9 | 7/7 |
Age (y) | 27 (24–37) | 27 (26–42)* | 24 (22–30)* |
BMI | 24 (22–26) | 23 (22–26) | 24 (23–26) |
Regular ICS use (n) | 15 | 6 | 9 |
FEV1 Baseline (% predicted) | 96 (90–104) | 95 (88–103) | 95 (92–105) |
Early drop in FEV1 (%) | 23 (21–25) | 22 (21–25) | 23 (21–25) |
Max. drop in FEV1 after 4–8 h (%) | 10 (7–17) | 7 (5–9) | 20 (15–24) |
Allergen used in challenge (n) (Cat/Horse/HDM/ Birch/Grass) | 17/6/2/4/3 | 10/4/1/2/1 | 7/2/1/2/2 |