Determinants of blood eosinophil levels in the general population and patients with COPD: a population-based, epidemiological study

Table 3 Multivariate analysis of the factors associated with the BEC

Parameter	Univariate	Multivariate
Parameter	P value	Estimate (standard error)	P value
Intercept		208.09 (31.01)	< 0.0001
Age (years)	0.4555
Sex
Female	Reference	Reference
Male	< 0.0001	30.98 (10.65)	0.0038
BMI (kg/m²)	0.8615
Smoking
Never smoker	Reference	Reference
Former smoker	0.0620	10.97 (12.73)	0.3892
Active smoker	0.0081	31.21 (13.68)	0.0229
Asthma
No	Reference	Reference
Yes	0.0274	36.91 (16.83)	0.0288
CAT score	0.1159
FEV1 (%)	0.0002	− 0.53 (0.28)	0.0543
DLCO (%)	0.0474
YPAS score	0.0493
6 MWD, m	0.3057
Exacerbations last year	0.0331
COPD
No	Reference
Yes	0.0003
Treatment with ICS	0.0099
Platelets, cells/µl	0.1026
Fibrinogen (g/L)	0.9357
CRP (mg/dL)	0.0831
Total emphysema volume (%)	0.0082	0.94 (0.51)	0.0660
% Airway wall area (Primary Bronchi)	0.4094
% Airway wall area (Secondary bronchi)	0.1527

BMI body mass index, CAT COPD assessment test, FEV1 forced expiratory volume in the first second, FVC forced vital capacity, DLCO diffusion capacity of the lung for carbon monoxide, 6MWD 6-min walk distance, YPAS Yale Physical Activity Questionnaire, CRP C-reactive protein. Values in bold are statistically significant. R-Square = 0.067

ISSN: 1465-993X