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Table 1 Baseline characteristics of patients with COPD from the KOCOSS according to the presence of chronic bronchitis and BMI categories

From: Association of body mass index and COPD exacerbation among patients with chronic bronchitis

 

Total (N = 1264)

Non-CB

CB

P

BMI ≥ 25 (n = 230)

BMI < 25 (n = 583)

BMI ≥ 25 (n = 98)

BMI < 25 (n = 353)

Age, years

69.1 ± 7.8

68.9 ± 7.4

69.9 ± 7.7

67.5 ± 7.9

68.3 ± 8.0

0.003

Sex, male

1150 (91.0)

200 (87.0)

536 (91.9)

89 (90.8)

325 (92.1)

0.095

Smoking status (N = 1260)

0.002

 Current smoker

327 (26.0)

48 (20.9)

133 (23.0)

27 (27.6)

119 (33.7)

 

 Ex-smoker

818 (64.9)

153 (66.5)

391 (67.5)

63 (64.3)

211 (59.8)

 

 Never smoker

115 (9.1)

29 (12.6)

55 (9.5)

8 (8.2)

23 (6.5)

 

Education (N = 1260)

0.118

 Middle school or less

727 (57.7)

122 (53.0)

327 (56.4)

58 (59.2)

220 (62.5)

 

 High school or more

533 (42.3)

108 (47.0)

253 (43.6)

40 (40.8)

132 (37.5)

 

Area of residence (N = 1223)

0.555

 Urban area

481 (39.3)

144 (63.4)

338 (60.4)

51 (54.8)

209 (60.9)

 

 Rural area

742 (60.7)

83 (36.6)

222 (39.6)

42 (45.2)

134 (39.1)

 

CAT score (N = 1253)

15.2 ± 7.8

12.8 ± 6.80

13.3 ± 7.05

16.6 ± 7.34

19.4 ± 8.07

< 0.0001

 CAT score ≥ 10

931 (74.3)

151 (65.9)

387 (67.2)

81 (83.5)

312 (88.9)

< 0.0001

mMRC grade  (N = 1263)

1.43 ± 0.90

1.26 ± 084

1.37 ± 0.91

1.43 ± 0.86

1.65 ± 0.90

< 0.0001

 mMRC grade ≥ 2

495 (39.2)

72 (31.3)

209 (35.8)

40 (40.8)

174 (49.4)

< 0.0001

SGRQ-C (N = 1259)

 

 Symptom

44.6 ± 20.6

36.2 ± 16.0

37.2 ± 17.6

55.4 ± 19.5

59.4 ± 18.7

< 0.0001

 Activity

46.1 ± 23.6

40.7 ± 21.0

44.0 ± 23.3

46.7 ± 22.5

53.1 ± 24.5

< 0.0001

 Impact

24.4 ± 19.6

18.6 ± 16.4

20.5 ± 17.1

29.3 ± 20.2

33.3 ± 21.7

< 0.0001

 Total

34.3 ± 18.9

28.1 ± 15.7

30.3 ± 17.2

38.8 ± 18.6

43.6 ± 20.0

< 0.0001

Exacerbation in the previous year (N = 1253)a

309 (24.7)

41 (17.9)

137 (23.7)

21 (21.6)

110 (31.4)

0.002

History of asthma (N = 1253)

473 (37.7)

86 (37.4)

224 (39.0)

32 (33.0)

131 (37.3)

0.722

Charlson comorbidity index (CCI)

2.13 ± 1.49

2.35 ± 1.42

2.16 ± 1.61

2.08 ± 1.28

1.94 ± 1.34

0.010

 CCI ≥ 3

363 (28.7)

89 (38.7)

162 (27.8)

26 (26.5)

86 (24.4)

0.002

  1. Data are presented as mean ± standard deviation or number (%). P values < 0.05 are presented in bold
  2. BMI, body mass index; CAT, COPD assessment test; CB, chronic bronchitis; CCI, Charlson comorbidity index; COPD, chronic obstructive pulmonary disease; KOCOSS, Korean COPD Subgroup Study; mMRC, modified medical research council; SGRQ-C, COPD-specific St. George’s Respiratory Questionnaire
  3. aNumber (%) of the patients who experienced at least one moderate or severe acute exacerbation in the year prior to enrollment