Skip to main content
Fig. 4 | Respiratory Research

Fig. 4

From: Effect of indacaterol/glycopyrronium on ventilation and perfusion in COPD: a randomized trial

Fig. 4

Effect of IND/GLY treatment on lung function—PD set. Analysis of IND/GLY treatment on A FEV1 and B FEF25–75% over time. Measurements were obtained 0.75 and 0.25 h pre-dose, and 0.25, 1 and 2 h post-dose on Day 1, and 0.75 and 0.25 h pre-dose and 0.25, 1 and 2 h post-dose on Day 8. C The effects of 8 days of IND/GLY versus placebo treatment on residual volume and inspiratory capacity are shown. Data were analyzed using a mixed-effects model including crossover sequence, period, treatment, and time as fixed factors, and patients as a random effect. *P < 0.0001. FEV1 forced expiratory volume in 1 s, FEF forced expiratory flow, IND/GLY indacaterol/glycopyrronium, SE standard error

Back to article page