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Table 4 Clinical outcomes of the study patients according to status of coronary artery disease and sex

From: Clinical and economic burden of comorbid coronary artery disease in patients with acute exacerbation of chronic obstructive pulmonary disease: sex differences in a nationwide cohort study

Clinical outcomes

CAD (n = 664)

No CAD (n = 3242)

P-value

Men

Women

CAD (n = 500)

No CAD (n = 2564)

P-value

CAD (n = 164)

No CAD (n = 678)

P-value

Length of hospital stay (days)

10.0 (5.8)

9.0 (4.0)

< 0.001

10.0 (5.0)

9.0 (5.0)

 < 0.001

9.0 (5.0)

9.0 (4.0)

0.122

Total cost during hospitalization (US$)

1419.3 (952.4)

1352.1 (862.1)

0.002

1502.2 (987.3)

1373.4 (886.6)

 < 0.001

1197.0 (812.3)

1289.4 (756.6)

0.421

Change of CAT at discharge compared to admission

− 8.0 (9.0)

− 7.0 (9.0)

0.003

− 8.0 (9.0)

− 7.0 (9.0)

0.006

− 8.0 (8.0)

− 7.0 (9.0)

0.235

CAT at day 30

11.0 (9.0)

11.0 (8.0)

0.020

12.0 (9.0)

11.0 (8.0)

0.046

11.0 (7.0)

10.0 (9.0)

0.194

mMRC at day 30

2.0 (1.0)

1.0 (1.0)

< 0.001

2.0 (1.0)

1.0 (1.0)

0.003

2.0 (1.0)

1.0 (1.0)

0.007

St George’s Respiratory Questionnaire at day 30

 Symptoms

52.4 (21.0)

53.6 (18.0)

0.225

52.6 (20.0)

54.0 (18.0)

0.659

49.3 (19.0)

52.2 (18.0)

0.108

 Activities

41.8 (31.0)

42.6 (30.0)

0.812

41.8 (37.0)

47.2 (30.0)

0.868

42.3 (37.0)

41.8 (30.0)

0.870

 Impacts

14.2 (25.0)

14.1 (24.0)

0.936

14.3 (25.0)

14.1 (24.0)

0.832

12.9 (23.0)

14.3 (23.0)

0.842

 Total

29.3 (23.0)

30.0 (22.0)

0.764

29.7 (23.0)

30.3 (22.0)

0.986

27.9 (21.0)

29.6 (22.0)

0.595

 All-cause readmission or death within 30 days

13 (3.1%)

68 (3.4%)

0.770

11 (3.4%)

59 (3.7%)

0.872

2 (2.0%)

9 (2.2%)

1.000

 AECOPD readmission within 30 days

11 (2.7%)

47 (2.4%)

0.861

9 (2.8%)

40 (2.5%)

0.846

2 (2.1%)

7 (1.7%)

0.686

  1. CAD coronary artery disease, CAT COPD Assessment Test, mMRC modified Medical Research Council, AECOPD acute exacerbations of chronic obstructive pulmonary disease
  2. Data are presented as n (%) or median (IQR)