Table 2 Patient characteristics on the day of the first spontaneous breathing trial (N = 787)
From: Comparison between pressure support ventilation and T-piece in spontaneous breathing trials
T-piece group (n = 473) | PSV group (n = 314) | p-value | |
|---|---|---|---|
Duration of MV before first spontaneous breathing trial, days | 5 (3–7) | 5 (4–7) | 0.225 |
Weak cough capacity | 67 (18.9) | 49 (19.8) | 0.799 |
Abundant tracheal secretions | 25 (7.1) | 17 (6.9) | 0.922 |
Artificial airway | 0.220 | ||
Endotracheal tube | 375 (79.3) | 260 (82.8) | |
Tracheostomy | 98 (20.7) | 54 (17.2) | |
Medical management | |||
Vasoactive drug | 87 (19.2) | 26 (8.5) | < 0.001 |
Sedatives | 190 (41.9) | 138 (45.0) | 0.397 |
Opioid | 357 (78.6) | 213 (69.4) | 0.004 |
Steroid | 212 (46.7) | 137 (44.6) | 0.574 |
Diuretics | 178 (39.2) | 113 (36.8) | 0.504 |
Renal replacement therapy | 57 (12.6) | 55 (17.9) | 0.041 |
RASS score | 0.659 | ||
RASS − 1–+ 1 | 332 (73.3) | 232 (75.6) | |
RASS < − 1 | 106 (23.4) | 68 (22.2) | |
RASS > + 1 | 15 (3.3) | 7 (2.3) | |
SOFA scores | 7 (4–9) | 7 (5–10) | 0.197 |
Setting of MV | |||
Mode | 0.251 | ||
Volume controlled ventilation | 0 (0.0) | 1 (0.3) | |
Pressure controlled ventilation | 48 (10.6) | 27 (8.8) | |
Synchronized intermittent mandatory ventilation | 0 (0.0) | 1 (0.3) | |
Pressure support ventilation | 406 (89.4) | 278 (90.6) | |
Peak inspiratory pressure, cmH2O | 16 (14–22) | 16 (14–18) | 0.142 |
Respiratory rate, breath/min | 18 (14–19) | 18 (14–23) | 0.258 |
PEEP, cmH2O | 5 (5–5) | 5 (5–5) | 0.266 |
Monitored Vt/PBW, mL/kg | 8.1 (6.3–10.1) | 7.1 (5.8–9.2) | 0.001 |
FiO2, % | 30 (30–40) | 30 (25–40) | 0.003 |
PaO2/FiO2 ratio | 288 (223–375) | 300.5 (230–391.7) | 0.135 |
Arterial blood gas | |||
pH | 7.457 (7.420–7.494) | 7.471 (7.436–7.500) | 0.008 |
PaCO2, mmHg | 35.5 (31.0–41.9) | 33.9 (29.2–40.2) | 0.063 |
PaO2, mmHg | 91.8 (78.9–106.1) | 90.0 (79.9–103.2) | 0.790 |
SaO2, % | 97.0 (95.6–98.4) | 97.0 (95.7–98.0) | 0.149 |
Lactate, mmol/L | 1.69 (1.14–2.32) | 2.01 (1.26–2.46) | 0.263 |