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Table 1 Patient characteristics and number of obtained samples

From: Identification of targetable kinases in idiopathic pulmonary fibrosis

IPF

Age (years)

Sex

Smoking history (pack-years)

Time from IPF diagnosis to surgery

IPF treatment

Lung cancer type

Gene analysis of lung cancer

Surgical procedure

Number of samples

Case 1

57

Male

132

7 years

None

SCC*

NA

Lung transplantation

6

Case 2

67

Male

23.5

4 years

None

SCC

EGFR-

Lobectomy

3

Case 3

61

Male

82.5

5 years

Pirfenidone

–

NA

Lung transplantation

2

Case 4

56

Male

82.5

3 months

None

SCC

NA

Lobectomy

1

Case 5

56

Male

36

3 weeks

None

SCC

NA

Lobectomy

1

Control

         

Case 1

45

Male

15

–

–

ADC

EGFR Ex18 G719S

Lobectomy

2

Case 2

82

Male

45

–

–

SCC

NA

Lobectomy

2

Case 3

65

Female

22.5

–

–

ADC

KRAS Q61H

Lobectomy

2

Case 4

63

Female

0

–

–

ADC

EGFR-

Lobectomy

2

  1. IPF idiopathic pulmonary fibrosis, SCC squamous cell carcinoma, ADC adenocarcinoma, EGFR epidermal growth factor receptor, KRAS Kirsten rat sarcoma viral oncogene homolog, NA not available
  2. *Lobectomy was performed seven years prior to lung transplantation