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Fig. 1 | Respiratory Research

Fig. 1

From: Tetracycline ameliorates silica-induced pulmonary inflammation and fibrosis via inhibition of caspase-1

Fig. 1

Tetracycline inhibits silica induced IL-1β production and pyroptosis. Murine BMDM were stimulated with either LPS (30 ng/ml) alone or in combination with silica (SIL, 1 mg/ml) and then treated with increasing doses of tetracycline (TET). IL-1ß (A), LDH B and TNF-α C concentrations were measured in supernatants with ELISA or LDH-Assay. Median with interquartile range of ≥ 4 independent experiments. Ranksum-testing adjusting for multiple comparison after Kruskal–Wallis test

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