Table 2 Measures of airway intra- and extra-cellular iron, and potential iron-regulatory proteins
From: Iron in airway macrophages and infective exacerbations of chronic obstructive pulmonary disease
Serum/sputum variables | AECOPD | Post-AECOPD | p-value |
|---|---|---|---|
Sputum hemosiderin index (%) | 2.5 (1.0,8.8) | 14.0 (4.3,31.0) | 0.0001 |
Sputum free iron (μM) | 3.1 ± 0.8 | 2.6 ± 0.7 | 0.015 |
Serum IL-6 (pg/mL) | 2.8 (2.3,36.6) | 3.4 (2.2,10.7) | 0.94 |
Sputum IL-6 (pg/mL) | 63.4 (11.5,211.0) | 111.0 (34.2, 198.0) | 0.19 |
Serum Hepcidin (ng/mL) | 77.8 (18.9,111.4) | 24.8 (4.6,79.6) | 0.01 |
Sputum Hepcidin (pg/mL) | 31.1 (8.0,71.8) | 15.5 (6.2,29.1) | 0.16 |