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Table 2 Demographics and clinical characteristics between the immunotherapy responder and non-responder groups

From: Relationship of the lung microbiome with PD-L1 expression and immunotherapy response in lung cancer

Characteristics

Responder

Non-responder

Total

P-value

No

8 (72.7)

3 (27.3)

11 (100.0)

 

Age

63.0 (54.5, 73.8)

62.0 (50.0, 62.0)

63.0 (54.0, 74.0)

0.840

Gender

   

0.491

 Male, n (%)

7 (87.5)

2 (66.7)

9 (81.8)

 

 Female, n (%)

1 (12.5)

1 (33.3)

2 (18.2)

 

Smoking history

   

0.179

 Current or former, n (%)

7 (87.5)

2 (66.7)

9 (81.8)

 

 Never, n (%)

1 (12.5)

1 (33.3)

2 (18.2)

 

Pack-years

35.0 (30.0, 40.0)

41.5 (33.0, 41.5)

35.0 (30.0, 45.0)

0.526

Neutrophil–lymphocyte ratio

2.63 (2.13, 4.36)

1.98 (1.86, 1.98)

2.27 (1.98, 3.76)

0.133

PD-L1 ≥ 10%

2 (25.0)

1 (33.3)

  

PD-L1 < 10%

6 (75.0)

2 (66.7)

  

Stage

   

0.361

 I/II/III/IV, n

0/0/4/4

0/0/1/2

0/0/5/6

 

Pathologic diagnosis

   

0.661

 Adenocarcinoma, n (%)

6 (75.0)

2 (66.7)

8 (72.7)

 

 Squamous cell carcinoma, n (%)

2 (25.0)

1 (33.3)

3 (27.3)

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