Table 1 Demographics and clinical characteristics of patients
From: Relationship of the lung microbiome with PD-L1 expression and immunotherapy response in lung cancer
Characteristics | PD-L1 < 10% | PD-L1 ≥ 10% | Total | P-value |
|---|---|---|---|---|
No | 59 (70.2) | 25 (29.8) | 84 (100.0) | Â |
Age (year) | 68.1 ± 10.7 | 63.1 ± 12.9 | 66.7 ± 11.2 | 0.080 |
Gender | Â | Â | Â | 0.797 |
 Male, n (%) | 36 (61.0) | 16 (64.0) | 52 (61.9) |  |
 Female, n (%) | 23 (39.0) | 9 (36.0) | 32 (38.1) |  |
Smoking history | Â | Â | Â | 0.574 |
 Current or former, n (%) | 32 (54.2) | 16 (64.0) | 48 (57.1) |  |
 Never, n (%) | 27 (45.8) | 9 (36.0) | 36 (42.9) |  |
Smoking amount (pack-years) | 32.1 ± 15.6 | 30.2 ± 15.5 | 31.5 ± 15.4 | 0.687 |
Immunotherapy responder | 6 (10.2) | 2 (8.0) | Â | Â |
Immunotherapy non-responder | 2 (3.4) | 1 (4.0) | Â | Â |
Neutrophil–Lymphocyte ratio | 2.93 (1.94, 6.13) | 3.14 (1.76, 5.09) | 3.05 (1.91, 5.85) | 0.889 |
Stage | Â | Â | Â | 0.084 |
 I/II/III/IV, n | 24/5/14/16 | 3/4/9/9 | 27/9/23/25 |  |
Pathologic diagnosis | Â | Â | Â | 0.979 |
 Adenocarcinoma, n (%) | 45 (76.3) | 19 (76.0) | 64 (76.2) |  |
 Squamous cell carcinoma, n (%) | 14 (23.7) | 6 (24.0) | 20 (23.8) |  |